Substrate and mechanotransduction influence SERCA2a localization in human pluripotent stem cell-derived cardiomyocytes affecting functional performance
Physical cues are major determinants of cellular phenotype and evoke physiological and pathological responses on cell structure and function.Cellular models aim to recapitulate basic functional features of their in vivo counterparts or tissues in order to be of use in in vitro disease modeling or drug screening and testing.Understanding how culture